To attack; to infringe; to encroach on; to violate.
To move into.
To enter by force in order to conquer.
To infest or overrun.
To make an unwelcome or uninvited visit or appearance, usually with an intent to cause trouble or some other unpleasant situation.
To perforate with a trephine.
To use a trephine during surgery.
A surgical instrument with a cylindrical blade used to remove a circular section of tissue, f.e. bone or cornea; a trepan.