To lower the morale of; to make despondent; to dishearten.
To ruin; wreck; mess up; screw up; sometimes as a bowdlerized substitution for fuck up.
To raise, hoist, or lift a thing using a jack, or similar means.
To raise, increase, or accelerate; often said of prices, fees, or rates.
To organise something.
To shoot, especially in the context of a poor shot opportunity.