To be hopeless; to have no hope; to give up all hope or expectation.
To cause to despair.
That which causes despair.
Loss of hope; utter hopelessness; complete despondency.
That which is despaired of.
Hopefully; a self-directive to undertake the customary action to ward off bad luck.
To take a customary action to ward off some misfortune that is believed to be attracted by a presumptuous statement.