A book containing such a text.
The text of a dramatic musical work, such as an opera.
A single, original copy of a book, article, composition etc, written by hand or even printed, submitted as original for (copy-editing and) reproductive publication.
A book, composition or any other document, written by hand (or manually typewritten), not mechanically reproduced.
Handwritten, or by extension manually typewritten, as opposed to being mechanically reproduced.