lifeblood vs substance

lifeblood

noun
  • That which is required for continued existence or function. 

  • Blood that is needed for continued life; blood regarded as the seat of life. 

substance

noun
  • A form of matter that has constant chemical composition and characteristic properties. 

  • Physical matter; material. 

  • Material possessions; estate; property; resources. 

  • Hypostasis. 

  • Drugs (illegal narcotics) 

  • Substantiality; solidity; firmness. 

  • The essential part of anything; the most vital part. 

verb
  • To give substance to; to make real or substantial. 

How often have the words lifeblood and substance occurred in a corpus of books? (source: Google Ngram Viewer )