locoregional vs systemic

locoregional

adj
  • Restricted to a localized region of the body. 

systemic

adj
  • Pertaining to an entire organism. 

  • Embedded within and spread throughout and affecting a whole system, group, body, economy, market, or society. 

How often have the words locoregional and systemic occurred in a corpus of books? (source: Google Ngram Viewer )