To abandon someone without warning.
To miss school, play truant, play hooky.
To crash or glitch.
To leave (a place) hastily.
To freak out, to go crazy, e.g. from worry.
To cause to bulge.
A rapid retreat, a rout.
To cease to behave in a consistent and/or rational manner.
To lose sight of an important objective or principle; to act contrarily to one's own interests through concentrating on relatively unimportant matters.
Used other than figuratively or idiomatically: see lose, plot.