Bitterness of temper; ill humour; irascibility.
A bitter brownish-yellow or greenish-yellow secretion produced by the liver, stored in the gall bladder, and discharged into the duodenum where it aids the process of digestion.
Two of the four humours, black bile or yellow bile, in ancient and medieval physiology.
The quality of being malign or malignant; badness, evilness, monstrosity, depravity, maliciousness.
A non-benign cancer; a malignancy.