The quality of being malign or malignant; badness, evilness, monstrosity, depravity, maliciousness.
A non-benign cancer; a malignancy.
Indecency; corruption; unkindness, meanness, spite, harshness, cruelty.
Lack of cleanliness.
Dirt, filth.
A nasty action, object, quality, etc. (all senses of nasty).
Unpleasantness, disagreeableness (to the senses).