To influence or control someone in order to achieve a specific purpose, especially one that is unknown to the one being manipulated and beneficial to the manipulator; to use
To move, arrange or operate something using the hands
To handle and move a body part, either as an examination or for a therapeutic purpose
To influence, manage, direct, control or tamper with something
To manipulate a situation, especially by asking favours of others; to use one's influence with others to attain a desired goal.
To control a person, organization, or situation by operating behind the scenes, as a puppeteer controls a marionette.