To influence, manage, direct, control or tamper with something
To influence or control someone in order to achieve a specific purpose, especially one that is unknown to the one being manipulated and beneficial to the manipulator; to use
To move, arrange or operate something using the hands
To handle and move a body part, either as an examination or for a therapeutic purpose
To abandon, forsake, discontinue (an action, habit, intention, etc), sometimes by open declaration.
To cast off, repudiate.
To fail to follow suit; playing a card of a different suit when having no card of the suit led.
To make a renunciation of something.
To give up, resign, surrender.
To surrender formally some right or trust.
To decline further association with someone or something, disown.
An act of renouncing.