calmative vs materia medica

calmative

noun
  • A drug with calming effects. 

adj
  • Calming. 

materia medica

noun
  • Synonym of medicine: the substances so used, particularly traditional cures prepared from animals and plants such as herbal medicines but inclusive of early drugs. 

  • Synonym of pharmacology, particularly its development in early modern Europe. 

How often have the words calmative and materia medica occurred in a corpus of books? (source: Google Ngram Viewer )