mutation vs vicissitude

mutation

noun
  • Any alteration or change. 

  • An alteration a particular sound of a word, especially the initial consonant, which is triggered by the word's morphological or syntactic context and not by its phonological context. 

  • A group of thrushes. 

  • A mutant. 

  • Any heritable change of the base-pair sequence of genetic material. 

vicissitude

noun
  • A change, especially in one's life or fortunes. 

  • Regular change or succession from one thing to another, or one part of a cycle to the next; alternation; mutual succession; interchange. 

How often have the words mutation and vicissitude occurred in a corpus of books? (source: Google Ngram Viewer )