To use a narcotic in order to make (someone) drowsy or insensible; to anesthetize, to drug.
To make into a narcotic.
To dull the senses of (a person, place etc.).
To injure or obstruct intentionally.
To steal.
To tamper with (typically a racehorse or greyhound) in order to prevent from winning a race.
To gain influence by corrupt means or intimidation.
A deliberate act of injury or obstruction.