To use a narcotic in order to make (someone) drowsy or insensible; to anesthetize, to drug.
To make into a narcotic.
To dull the senses of (a person, place etc.).
To give a general anesthetic prior to surgery.
To help (someone) to bed; put to bed.
To kill an animal painlessly, often with an injection; to euthanize.
To cause (someone) to sleep.
To render dormant.