In a screwed up or messed up manner; (by extension) under the influence of alcohol or drugs.
All wrong; mistaken; taken the wrong way
Damaged; poorly manufactured; injured.
In disarray or dishevelment (emotionally or otherwise).
Drunk; wasted; incredibly intoxicated (not necessarily with alcohol).
Misconstrued or misunderstood; taken the wrong way
Morally reprehensible; clearly and grossly objectionable.
Free from work or direct supervision.
Crazy and exciting; delirious and wild.