Feeling mildly unwell.
Dirty, vulgar or obscene, especially in a way that is unpleasant.
Different than usual.
Of the wrong color.
Of a person: having obtained worldly experience, and lacking naiveté; cosmopolitan, worldly-wise.
Complicated, especially of complex technology.
Of art or other things: appealing to the tastes of an intellectual or sophisticated (sense 1) person; cerebral; also, cultured, elegant, refined.