To annoy, cause discomfort or resent.
To transgress or violate a law or moral requirement.
To hurt the feelings of; to displease; to make angry; to insult.
To feel or become offended; to take insult.
To physically harm, pain.
To sin, transgress divine law or moral rules.
To cause irritation or deep bitterness.
To fester.
A festering, embittering object or condition, either mental, or a physical sore or ulcer.