A situation whereby several problems come together and make everything worse.
A powerful hurricane or other major weather disturbance, especially as produced by a combination of meteorological conditions.
Someone (especially a woman) who is unbalanced and considered a mess, a disaster, one who is suffering personal ruin.
The aftermath of a train crash.
A disaster, especially one which is large in scale and readily seen by public observers.
To ruin utterly and catastrophically, to cause to end in disaster.