A product or manufactured article, especially an item of art or craft.
A person who has a strong and unusual personality, especially one with seriously unpleasant character flaws (e.g. a nasty piece of work). (This sense came about due to Hamlet’s soliloquy (see sense 1 above)).
A piece of work done as part of one’s duties.
Any piece of work done.
A difficult or tedious undertaking.
A process or execution of a program.
An objective.
To charge, as with a fault.
To assign a task to, or impose a task on.
To oppress with severe or excessive burdens; to tax