To ignore (a comment, etc.).
To dismiss from employment.
To release from one's grasp; to go from a state of holding on to a state of no longer holding on.
To emotionally disengage or to distract oneself from a situation.
To fail to maintain a standard of appearance, behavior, or performance.
Used other than figuratively or idiomatically: see let, go.
To gain weight
To ignore proper behavior or social conventions, especially when it suits one's purpose.
To act in a tricky, inconstant way, saying one thing and doing another.
To be recklessly inaccurate, inappropriate, or otherwise ignoring guidelines and conventions.