To control (a machine, vehicle, situation, etc.) by means of physical strength.
To mishandle; to handle roughly; to mangle.
To move something heavy by force of men, without aid of levers, pulleys, machine, or tackles.
To assault or beat up a person.
To fiddle with; make small adjustments to, for example to something mechanical in order to improve its performance.
To trick.
To sexually stimulate a person or a person's erogenous zone.
Used other than figuratively or idiomatically: play with.