To do something that is especially difficult or effortful.
To remove teeth, usually because they are diseased or damaged.
To take upon oneself; to start, to embark on (a specific task etc.).
To commit oneself (to an obligation, activity etc.).
To pass a slower moving vehicle on the curbside rather than on the side closest to oncoming traffic.
The passing of slower traffic on the curbside rather than on the side closest to oncoming traffic.