patient vs refractory

patient

adj
  • Constant in pursuit or exertion; persevering; calmly diligent. 

  • Willing to wait if necessary; not losing one's temper while waiting. 

noun
  • One who, or that which, is passively affected; a passive recipient. 

  • A person or animal who receives treatment from a doctor or other medically educated person. 

  • The noun or noun phrase that is semantically on the receiving end of a verb's action. 

refractory

adj
  • Obstinate and unruly; strongly opposed to something. 

  • Not affected by great heat. 

  • Difficult to treat. 

  • Incapable of registering a reaction or stimulus. 

noun
  • A material or piece of material, such as a brick, that has a very high melting point. 

How often have the words patient and refractory occurred in a corpus of books? (source: Google Ngram Viewer )