area vs region

area

noun
  • Any particular extent of surface, especially an empty or unused extent. 

  • A particular geographic region. 

  • An open space, below ground level, giving access to the basement of a house, and typically separated from the pavement by railings. 

  • The extent, scope, or range of an object or concept. 

  • Genitals. 

  • A measure of the extent of a surface; it is measured in square units. 

  • Penalty box; penalty area. 

region

noun
  • Any considerable and connected part of a space or surface; specifically, a tract of land or sea of considerable but indefinite extent; a country; a district; in a broad sense, a place without special reference to location or extent but viewed as an entity for geographical, social or cultural reasons. 

  • A subnational region of Chile; equivalent to province. 

  • An administrative subdivision of the European Union. 

  • A subprovincial region of Quebec; the primary level subdivision; a prefecture. 

  • The inhabitants of a region or district of a country. 

  • A place in or a part of the body in any way indicated. 

  • Such a division of the city of Rome and of the territory about Rome, of which the number varied at different times; a district, quarter, or ward. 

How often have the words area and region occurred in a corpus of books? (source: Google Ngram Viewer )