To render insane.
To poison with the loco plant; to affect with locoism.
Crazy.
Intoxicated by eating locoweed.
A certain species of Astragalus or Oxytropis, capable of causing locoism.
A locomotive.
A direction in written or printed music to be returning to the proper pitch after having played an octave higher or lower.
Crazy, mad or insane.
Close to or in close proximity to another location.