To severely disrupt the well-being of (a person); ruin.
To sing a song poorly.
To put down or euthanize.
To remove data.
To exhaust duly and thus recreate or build up.
To penetrate sexually in an aggressive way.
To damage beyond use or repair.
To defeat soundly.
To neutralize, undo a property or condition.
To make a painful situation even worse (even with the best of intentions).