A scream.
Loud, sharp, and piercing to the ear.
Hilariously funny; calculated to make people roar with laughter.
Effeminate, flamboyant or otherwise obviously gay.
Obvious; distinct.
First-rate; splendid.
Someone suicidal; someone likely to kill themselves.
Likely to commit, or to attempt to commit, suicide.
Extremely reckless.
Highly likely to certain to result in the deaths of the participants; dangerous or reckless to such a degree as to be tantamount to suicide for those taking part.
Pertaining to suicide.