The cause of being ruined, destroyed or lost.
The state of being ruined, a state of devastation or destruction.
A loss of reputation.
The act of ruining or wrecking.
Old age; accumulated damage to macromolecules, cells, tissues and organs with the passage of time.
The state or process of ageing, especially in humans; old age.
Fruit senescence, leading to ripening of fruit.
Ceasing to divide by mitosis because of shortening of telomeres or excessive DNA damage.
Condition when the cell ceases to divide.