To give (something) a meaning or an importance.
To show one’s intentions with a sign etc.; to indicate, announce.
To mean; to betoken.
To make a difference; to matter (in negative or interrogative expressions).
To create a sign out of something.
To make (someone or something) no longer noble
Not noble; ignoble; base.
Of a metal, being at the lower end of the electrochemical series, i.e. oxidising readily.