The best or most substantial part of something.
A penis.
The flesh (muscle tissue) of an animal used as food.
Any relatively thick, solid part of a fruit, nut etc.
A type of meat, by anatomic position and provenance.
The sweet spot of a bat or club (in cricket, golf, baseball etc.).
A totem, or (by metonymy) a clan or clansman which uses it.
A meathead.
Something (food, water, money, etc.) that is required to stay alive.
Embodiment or personification or hypostasis of an underlying principle or quality.
Real being; existence.
Inherency.
The act of maintaining oneself at a minimum level.