The basic, central, or essential point or feature.
The critical or transitional moment or issue, a turning point.
The hardest point of a climb.
A puzzle or difficulty.
A cross on a coat of arms.
The essential part of anything; the most vital part.
Physical matter; material.
Material possessions; estate; property; resources.
Hypostasis.
Drugs (illegal narcotics)
Substantiality; solidity; firmness.
A form of matter that has constant chemical composition and characteristic properties.
To give substance to; to make real or substantial.