Most important; essential.
Not imaginary; real; actual; true; veritable.
Having a substance; actually existing.
Corporeal; material; firm.
Possessed of goods or an estate; moderately wealthy.
Satisfying; having sufficient substance to be nourishing or filling.
Large in size, quantity, or value; ample; significant.
Having good substance; strong; stout; solid; firm.
Anything having substance; an essential part.
Supernatural beings and events collectively (when used with definite article: "the supernatural")
A supernatural being
Not of the usual; not natural; altered by forces that are not understood fully if at all.
Above nature; beyond or added to nature, often so considered because it is given by a deity or some force beyond that which humans are born with.