The best or most substantial part of something.
A penis.
The flesh (muscle tissue) of an animal used as food.
Any relatively thick, solid part of a fruit, nut etc.
A type of meat, by anatomic position and provenance.
The sweet spot of a bat or club (in cricket, golf, baseball etc.).
A totem, or (by metonymy) a clan or clansman which uses it.
A meathead.
Something that provides support or nourishment.