To take action with respect to (someone or something).
To be in charge of, act on, or dispose of.
To behave in a certain way towards.
To consider, as an example.
To handle verbally or in some form of artistic expression; to address or discuss as a subject.
To come to terms with; to overcome any difficulties presented by.
To be courageous; to regain one's courage.
Used when encouraging someone to bear or take up a difficult situation.