To release from one's grasp; to go from a state of holding on to a state of no longer holding on.
To dismiss from employment.
To ignore (a comment, etc.).
To emotionally disengage or to distract oneself from a situation.
To fail to maintain a standard of appearance, behavior, or performance.
Used other than figuratively or idiomatically: see let, go.
To gain weight
To occupy, detain, keep busy, or delay.
To immobilize a capital: make a capital investment that makes that capital unavailable.
To complete, finish, or resolve.
Don't forget to tie up your hair before you bake.
To secure with rope, string, etc.