A collision where the front ends of two vehicles (such as ships, trains, cars, planes, etc.) hit each other, as opposed to a side-collision or rear-end collision.
The aftermath of a train crash.
A disaster, especially one which is large in scale and readily seen by public observers.
Someone (especially a woman) who is unbalanced and considered a mess, a disaster, one who is suffering personal ruin.
To ruin utterly and catastrophically, to cause to end in disaster.