tranquilize vs work up

tranquilize

verb
  • To make (something or someone) tranquil. 

  • To calm (a person or animal) or put them to sleep using a tranquilizer dart. 

work up

verb
  • To raise; to excite; to stir up. 

  • To give (a patient) a general medical examination to assess health and fitness. 

  • To develop. 

How often have the words tranquilize and work up occurred in a corpus of books? (source: Google Ngram Viewer )