hindrance vs tranquilizer

hindrance

noun
  • Something which hinders: something that holds back or causes problems with something else. 

  • The state or act of hindering something 

tranquilizer

noun
  • That which tranquillizes or soothes. 

  • A drug used to reduce anxiety or tension. 

How often have the words hindrance and tranquilizer occurred in a corpus of books? (source: Google Ngram Viewer )