instigation vs tranquilizer

instigation

noun
  • The act of instigating, or the state of being instigated; incitement; especially to evil or wickedness. 

tranquilizer

noun
  • That which tranquillizes or soothes. 

  • A drug used to reduce anxiety or tension. 

How often have the words instigation and tranquilizer occurred in a corpus of books? (source: Google Ngram Viewer )