To have sex (with).
To carry (something), especially with some exertion.
To bend something into a hump.
To shunt wagons / freight cars over the hump in a hump yard.
To dry-hump.
A mound of earth.
An act of sexual intercourse.
A bad mood.
A speed bump or speed hump.
A wave that forms in front of an operating hovercraft and impedes progress at low speeds.
A rounded fleshy mass, such as on a camel or zebu.
A painfully boorish person.
A deformity in humans caused by abnormal curvature of the upper spine.
To perform a sexual service for a customer.