Of a person: having obtained worldly experience, and lacking naiveté; cosmopolitan, worldly-wise.
Complicated, especially of complex technology.
Of art or other things: appealing to the tastes of an intellectual or sophisticated (sense 1) person; cerebral; also, cultured, elegant, refined.
Not well developed.
Not formed or made.
Not having a definite form; shapeless; amorphous.
Not grouped into any constellation.
Decomposed, or resolved into parts; having the form destroyed.