A crucial or decisive point or situation; a turning point.
A traumatic or stressful change in a person's life.
A sudden change in the course of a disease, usually at which point the patient is expected to either recover or die.
A point in a drama at which a conflict reaches a peak before being resolved.
An unstable situation, in political, social, economic or military affairs, especially one involving an impending abrupt change.
The quality or condition of being urgent.
Insistence, pressure, urge.
A sudden and compelling need to urinate that is difficult to defer, associated with conditions such as urinary tract infections and overactive bladder.