bacterium vs vacuole

bacterium

noun
  • A single-celled organism with cell walls but no nucleus or organelles. 

vacuole

noun
  • A large membrane-bound vesicle in a cell's cytoplasm. 

  • A small empty or air-filled space or vacuity. 

How often have the words bacterium and vacuole occurred in a corpus of books? (source: Google Ngram Viewer )