follicle vs vacuole

follicle

noun
  • A small cavity or sac, such as a hair follicle. 

  • A type of primitive dry fruit produced by certain flowering plants. 

vacuole

noun
  • A large membrane-bound vesicle in a cell's cytoplasm. 

  • A small empty or air-filled space or vacuity. 

How often have the words follicle and vacuole occurred in a corpus of books? (source: Google Ngram Viewer )