lacuna vs vesicle

lacuna

noun
  • A space visible between cells, allowing free passage of light. 

  • Any gap, break, hole, or lack in a set of things; something missing. 

  • A language gap, which occurs when there is no direct translation in the target language for a lexical term found in the source language. 

  • An absent part, especially in a book or other piece of writing, often referring to an ancient manuscript or similar. 

  • A small blank space; a gap or vacancy; a hiatus. 

  • A small opening; a small pit or depression, especially in bone. 

vesicle

noun
  • A membrane-bound compartment found in a cell. 

  • A small sac or cyst or vacuole, especially one containing fluid. A blister formed in or beneath the skin, containing serum. A bleb. 

  • (usually and especially) Such a blister that is less than 5 mm in diameter. 

  • A small cavity formed in volcanic rock by entrapment of a gas bubble during solidification. 

  • A small sac filled with juice, one of many constituting the pulp of a fruit such as an orange, lemon, or grapefruit. 

  • A pocket of embryonic tissue that is the beginning of an organ. 

How often have the words lacuna and vesicle occurred in a corpus of books? (source: Google Ngram Viewer )