vesicle vs wheal

vesicle

noun
  • A small sac or cyst or vacuole, especially one containing fluid. A blister formed in or beneath the skin, containing serum. A bleb. 

  • (usually and especially) Such a blister that is less than 5 mm in diameter. 

  • A small cavity formed in volcanic rock by entrapment of a gas bubble during solidification. 

  • A membrane-bound compartment found in a cell. 

  • A small sac filled with juice, one of many constituting the pulp of a fruit such as an orange, lemon, or grapefruit. 

  • A pocket of embryonic tissue that is the beginning of an organ. 

wheal

noun
  • A small raised swelling on the skin, often itchy, caused by a blow from a whip or an insect bite etc. 

  • A mine. 

verb
  • Synonym of wale. 

How often have the words vesicle and wheal occurred in a corpus of books? (source: Google Ngram Viewer )